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Pfizer’s BEQVEZ Approved by FDA for Treatment of Adults with Hemophilia B

One-time treatment is designed to enable people living with hemophilia B to produce FIX themselves.

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By: Charlie Sternberg

Associate Editor

The U.S. Food and Drug Administration (FDA) has approved Pfizer’s BEQVEZ (fidanacogene elaparvovec-dzkt) for the treatment of adults with moderate to severe hemophilia B who currently use factor IX (FIX) prophylaxis therapy, or have current or historical life-threatening hemorrhage, or have repeated, serious spontaneous bleeding episodes, and do not have neutralizing antibodies to adeno-associated virus serotype Rh74var (AAVRh74var) capsid as detected by an FDA-approved test.   BEQVEZ is a one...

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